Biophysical probes reveal a “compromise” nature of the methyllysine binding pocket in L3MBTL1

od Gao, Cen, Herold, J. Martin, Kireev, Dmitri, Wigle, Tim, Norris, Jacqueline L., Frye, Stephen
Izdano 2011

The L3MBTL3 methyl-lysine reader domain functions as a dimer

od Baughman, Brandi M., Pattenden, Samantha G., Norris, Jacqueline L., James, Lindsey I., Frye, Stephen V.
izdano v ACS Chem Biol (2015)

Retraction of “The L3MBTL3 Methyl-Lysine Reader Domain Functions As a Dimer”

od Baughman, Brandi M., Pattenden, Samantha G., Norris, Jacqueline L., James, Lindsey I., Frye, Stephen V.
izdano v ACS Chem Biol (2017)

Accessing Protein Methyltransferase and Demethylase Enzymology Using Microfluidic Capillary Electrophoresis

od Wigle, Tim J., Provencher, Laurel M., Norris, Jacqueline L., Jin, Jian, Brown, Peter J., Frye, Stephen V., Janzen, William P.
Izdano 2010

Chromodomain Ligand Optimization via Target-Class Directed Combinatorial Repurposing

od Barnash, Kimberly D., Lamb, Kelsey N., Stuckey, Jacob I., Norris, Jacqueline L., Cholensky, Stephanie H., Kireev, Dmitri B., Frye, Stephen V., James, Lindsey I.
izdano v ACS Chem Biol (2016)

Small-Molecule Ligands of Methyl-Lysine Binding Proteins: Optimization of Selectivity for L3MBTL3

od James, Lindsey I., Korboukh, Victoria K., Krichevsky, Liubov, Baughman, Brandi M., Herold, J. Martin, Norris, Jacqueline L., Jin, Jian, Kireev, Dmitri B., Janzen, William P., Arrowsmith, Cheryl H., Frye, Stephen V.
Izdano 2013

The structure-activity relationships of L3MBTL3 inhibitors: flexibility of the dimer interface

od Camerino, Michelle A., Zhong, Nan, Dong, Aiping, Dickson, Bradley M., James, Lindsey I., Baughman, Brandi M., Norris, Jacqueline L., Kireev, Dmitri B., Janzen, William P., Arrowsmith, Cheryl H., Frye, Stephen V.
Izdano 2013

Discovery of a Selective, Substrate-Competitive Inhibitor of the Lysine Methyltransferase SETD8

od Ma, Anqi, Yu, Wenyu, Li, Fengling, Bleich, Rachel M., Herold, J. Martin, Butler, Kyle V., Norris, Jacqueline L., Korboukh, Victoria, Tripathy, Ashutosh, Janzen, William P., Arrowsmith, Cheryl H., Frye, Stephen V., Vedadi, Masoud, Brown, Peter J., Jin, Jian
Izdano 2014

Small Molecule Ligands of Methyl-Lysine Binding Proteins

od Herold, J. Martin, Wigle, Tim J., Norris, Jacqueline L., Lam, Robert, Korboukh, Victoria K., Gao, Cen, Ingerman, Lindsey A., Kireev, Dmitri B., Senisterra, Guillermo, Vedadi, Masoud, Tripathy, Ashutosh, Brown, Peter J., Arrowsmith, Cheryl H., Jin, Jian, Janzen, William P., Frye, Stephen V.
Izdano 2011

Expression of Ror2 Mediates Invasive Phenotypes in Renal Cell Carcinoma

od Rasmussen, Neal R., Debebe, Zufan, Wright, Tricia M., Brooks, Samira A., Sendor, Adam B., Brannon, A . Rose, Hakimi, A . Ari, Hsieh, James J., Choueiri, Toni K., Tamboli, Pheroze, Maranchie, Jodi K., Hinds, Peter, Wallen, Eric M., Simpson, Catherine, Norris, Jacqueline L., Janzen, William P., Rathmell, W. Kimryn
izdano v PLoS One (2014)

Identification of a Fragment-like Small Molecule Ligand for the Methyl-lysine Binding Protein, 53BP1

od Perfetti, Michael T., Baughma, Brandi M., Dickson, Bradley M., Mu, Yunxiang, Cui, Gaofeng, Mader, Pavel, Dong, Aiping, Norris, Jacqueline L., Rothbart, Scott B., Strahl, Brian D., Brown, Peter J., Janzen, William P., Arrowsmith, Cheryl H., Mer, Georges, McBride, Kevin M., James, Lindsey I., Frye, Stephen V.
izdano v ACS Chem Biol (2015)

Protein Lysine Methyltransferase G9a Inhibitors: Design, Synthesis, and Structure Activity Relationships of 2,4-Diamino-7-aminoalkoxy-quinazolines.

od Liu, Feng, Chen, Xin, Allali-Hassani, Abdellah, Quinn, Amy M., Wigle, Tim J., Wasney, Gregory A., Dong, Aiping, Senisterra, Guillermo, Chau, Irene, Siarheyeva, Alena, Norris, Jacqueline L., Kireev, Dmitri B., Jadhav, Ajit, Herold, J. Martin, Janzen, William P., Arrowsmith, Cheryl H., Frye, Stephen V., Brown, Peter J., Simeonov, Anton, Vedadi, Masoud, Jin, Jian
Izdano 2010

Discovery and Characterization of a Cellularly Potent Positive Allosteric Modulator of the Polycomb Repressive Complex 1 Chromodomain, CBX7

od Lamb, Kelsey N., Bsteh, Daniel, Dishman, Sarah N., Moussa, Hagar F., Fan, Huitao, Stuckey, Jacob I., Norris, Jacqueline L., Cholensky, Stephanie H., Li, Dongxu, Wang, Jingkui, Sagum, Cari, Stanton, Benjamin Z., Bedford, Mark T., Pearce, Kenneth H., Kenakin, Terry P., Kireev, Dmitri B., Wang, Gang Greg, James, Lindsey I., Bell, Oliver, Frye, Stephen V.
izdano v Cell Chem Biol (2019)

Discovery of a chemical probe for the L3MBTL3 methyl-lysine reader domain

od James, Lindsey I., Barsyte-Lovejoy, Dalia, Zhong, Nan, Krichevsky, Liubov, Korboukh, Victoria K., Herold, Martin J., MacNevin, Christopher J., Norris, Jacqueline L., Sagum, Cari A., Tempel, Wolfram, Marcon, Edyta, Guo, Hongbo, Gao, Cen, Huang, Xi-Ping, Duan, Shili, Emili, Andrew, Greenblatt, Jack F., Kireev, Dmitri B., Jin, Jian, Janzen, William P., Brown, Peter J., Bedford, Mark T., Arrowsmith, Cheryl H., Frye, Stephen V.
Izdano 2013

An Orally Bioavailable Chemical Probe of the Lysine Methyltransferases EZH2 and EZH1

od Konze, Kyle D., Ma, Anqi, Li, Fengling, Barsyte-Lovejoy, Dalia, Parton, Trevor, MacNevin°, Christopher J., Liu, Feng, Gao, Cen, Huang, Xi-Ping, Kuznetsova, Ekaterina, Rougie°, Marie, Jiang, Alice, Pattenden, Samantha G., Norris, Jacqueline L., James, Lindsey I., Roth, Bryan L., Brown, Peter J., Frye, Stephen V., Arrowsmith, Cheryl H., Hahn°, Klaus M., Wang, Gang Greg, Vedadi, Masoud, Jin, Jian
Izdano 2013

A cellular chemical probe targeting the chromodomains of Polycomb Repressive Complex 1

od Stuckey, Jacob I, Dickson, Bradley M, Cheng, Nancy, Liu, Yanli, Norris, Jacqueline L, Cholensky, Stephanie H, Tempel, Wolfram, Qin, Su, Huber, Katherine G, Sagum, Cari, Black, Karynne, Li, Fengling, Huang, Xi-Ping, Roth, Bryan L, Baughman, Brandi M, Senisterra, Guillermo, Pattenden, Samantha G, Vedadi, Masoud, Brown, Peter J, Bedford, Mark T, Min, Jinrong, Arrowsmith, Cheryl H, James, Lindsey I, Frye, Stephen V
izdano v Nat Chem Biol (2016)

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

od Vedadi, Masoud, Barsyte-Lovejoy, Dalia, Liu, Feng, Rival-Gervier, Sylvie, Allali-Hassani, Abdellah, Labrie, Viviane, Wigle, Tim J, Dimaggio, Peter A, Wasney, Gregory A, Siarheyeva, Alena, Dong, Aiping, Tempel, Wolfram, Wang, Sun-Chong, Chen, Xin, Chau, Irene, Mangano, Thomas J, Huang, Xi-ping, Simpson, Catherine D, Pattenden, Samantha G, Norris, Jacqueline L, Kireev, Dmitri B, Tripathy, Ashutosh, Edwards, Aled, Roth, Bryan L, Janzen, William P, Garcia, Benjamin A, Petronis, Arturas, Ellis, James, Brown, Peter J, Frye, Stephen V, Arrowsmith, Cheryl H, Jin, Jian
Izdano 2011