Unrestrained Computation of Free Energy along a Path

Por Dickson, Bradley M., Huang, He, Post, Carol Beth
Publicado em 2012

From Histones to Ribosomes: A Chromatin Regulator Tangoes with Translation

Por Rothbart, Scott B., Dickson, Bradley M., Strahl, Brian D.
Publicado no Cancer Discov (2015)

αC Helix as a Switch in the Conformational Transition of Src/CDK-like Kinase Domains

Por Huang, He, Zhao, Ruijun, Dickson, Bradley M., Skeel, Robert D., Post, Carol Beth
Publicado em 2012

A fast, open source implementation of adaptive biasing potentials uncovers a ligand design strategy for the chromatin regulator BRD4

Por Dickson, Bradley M., de Waal, Parker W., Ramjan, Zachary H., Xu, H. Eric, Rothbart, Scott B.
Publicado no J Chem Phys (2016)

Multivalent histone engagement by the linked tandem Tudor and PHD domains of UHRF1 is required for the epigenetic inheritance of DNA methylation

Por Rothbart, Scott B., Dickson, Bradley M., Ong, Michelle S., Krajewski, Krzysztof, Houliston, Scott, Kireev, Dmitri B., Arrowsmith, Cheryl H., Strahl, Brian D.
Publicado em 2013

Structure-activity relationships and kinetic studies of peptidic antagonists of CBX chromodomains

Por Stuckey, Jacob I., Simpson, Catherine, Norris-Drouin, Jacqueline L., Cholensky, Stephanie H., Lee, Junghyun, Pasca, Ryan, Cheng, Nancy, Dickson, Bradley M., Pearce, Kenneth H., Frye, Stephen V., James, Lindsey I.
Publicado no J Med Chem (2016)

The structure-activity relationships of L3MBTL3 inhibitors: flexibility of the dimer interface

Por Camerino, Michelle A., Zhong, Nan, Dong, Aiping, Dickson, Bradley M., James, Lindsey I., Baughman, Brandi M., Norris, Jacqueline L., Kireev, Dmitri B., Janzen, William P., Arrowsmith, Cheryl H., Frye, Stephen V.
Publicado em 2013

The structural basis of the dominant negative phenotype of the Gα(i1)β(1)γ(2) G203A/A326S heterotrimer

Por Liu, Ping, Jia, Ming-zhu, Zhou, X Edward, De Waal, Parker W, Dickson, Bradley M, Liu, Bo, Hou, Li, Yin, Yan-ting, Kang, Yan-yong, Shi, Yi, Melcher, Karsten, Xu, H Eric, Jiang, Yi
Publicado no Acta Pharmacol Sin (2016)

An interactive database for the assessment of histone antibody specificity

Por Rothbart, Scott B., Dickson, Bradley M., Raab, Jesse R., Grzybowski, Adrian T., Krajewski, Krzysztof, Guo, Angela H., Shanle, Erin K., Josefowicz, Steven Z., Fuchs, Stephen M., Allis, C. David, Magnuson, Terry R., Ruthenburg, Alexander J., Strahl, Brian D.
Publicado no Mol Cell (2015)

Identification of a Fragment-like Small Molecule Ligand for the Methyl-lysine Binding Protein, 53BP1

Por Perfetti, Michael T., Baughma, Brandi M., Dickson, Bradley M., Mu, Yunxiang, Cui, Gaofeng, Mader, Pavel, Dong, Aiping, Norris, Jacqueline L., Rothbart, Scott B., Strahl, Brian D., Brown, Peter J., Janzen, William P., Arrowsmith, Cheryl H., Mer, Georges, McBride, Kevin M., James, Lindsey I., Frye, Stephen V.
Publicado no ACS Chem Biol (2015)

Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1

Por Harrison, Joseph S, Cornett, Evan M, Goldfarb, Dennis, DaRosa, Paul A, Li, Zimeng M, Yan, Feng, Dickson, Bradley M, Guo, Angela H, Cantu, Daniel V, Kaustov, Lilia, Brown, Peter J, Arrowsmith, Cheryl H, Erie, Dorothy A, Major, Michael B, Klevit, Rachel E, Krajewski, Krzysztof, Kuhlman, Brian, Strahl, Brian D, Rothbart, Scott B
Publicado no eLife (2016)

A cellular chemical probe targeting the chromodomains of Polycomb Repressive Complex 1

Por Stuckey, Jacob I, Dickson, Bradley M, Cheng, Nancy, Liu, Yanli, Norris, Jacqueline L, Cholensky, Stephanie H, Tempel, Wolfram, Qin, Su, Huber, Katherine G, Sagum, Cari, Black, Karynne, Li, Fengling, Huang, Xi-Ping, Roth, Bryan L, Baughman, Brandi M, Senisterra, Guillermo, Pattenden, Samantha G, Vedadi, Masoud, Brown, Peter J, Bedford, Mark T, Min, Jinrong, Arrowsmith, Cheryl H, James, Lindsey I, Frye, Stephen V
Publicado no Nat Chem Biol (2016)