Chromodomain Ligand Optimization via Target-Class Directed Combinatorial Repurposing

od Barnash, Kimberly D., Lamb, Kelsey N., Stuckey, Jacob I., Norris, Jacqueline L., Cholensky, Stephanie H., Kireev, Dmitri B., Frye, Stephen V., James, Lindsey I.
Wydane w ACS Chem Biol (2016)

Discovery of an H3K36me3-Derived Peptidomimetic Ligand with Enhanced Affinity for Plant Homeodomain Finger Protein 1 (PHF1)

od Engelberg, Isabelle A., Liu, Jiuyang, Norris-Drouin, Jacqueline L., Cholensky, Stephanie H., Ottavi, Samantha A., Frye, Stephen V., Kutateladze, Tatiana G., James, Lindsey I.
Wydane w J Med Chem (2021)

Structure-activity relationships and kinetic studies of peptidic antagonists of CBX chromodomains

od Stuckey, Jacob I., Simpson, Catherine, Norris-Drouin, Jacqueline L., Cholensky, Stephanie H., Lee, Junghyun, Pasca, Ryan, Cheng, Nancy, Dickson, Bradley M., Pearce, Kenneth H., Frye, Stephen V., James, Lindsey I.
Wydane w J Med Chem (2016)

Degradation of Polycomb Repressive Complex 2 with an EED-targeted Bivalent Chemical Degrader

od Potjewyd, Frances, Turner, Anne-Marie W., Beri, Joshua, Rectenwald, Justin M, Norris-Drouin, Jacqueline L., Cholensky, Stephanie H., Margolis, David M., Pearce, Kenneth H., Herring, Laura E., James, Lindsey I.
Wydane w Cell Chem Biol (2019)

Discovery of Peptidomimetic Ligands of EED as Allosteric Inhibitors of PRC2

od Barnash, Kimberly D., The, Juliana, Norris-Drouin, Jacqueline L., Cholensky, Stephanie H., Worley, Beau M., Li, Fengling, Stuckey, Jacob I., Brown, Peter J., Vedadi, Masoud, Arrowsmith, Cheryl H., Frye, Stephen V., James, Lindsey I.
Wydane w ACS Comb Sci (2017)

Discovery and Characterization of Peptide Inhibitors for CIB1

od Puhl, Ana C., Bogart, Jonathan W., Haberman, Victoria A., Larson, Jacob E., Godoy, Andre S., Norris-Drouin, Jacqueline L., Cholensky, Stephanie H., Leisner, Tina M., Frye, Stephen V., Parise, Leslie V., Bowers, Albert A., Pearce, Kenneth H.
Wydane w ACS Chem Biol (2020)

Design and Construction of a Focused DNA-Encoded Library for Multivalent Chromatin Reader Proteins

od Rectenwald, Justin M., Guduru, Shiva Krishna Reddy, Dang, Zhao, Collins, Leonard B., Liao, Yi-En, Norris-Drouin, Jacqueline L., Cholensky, Stephanie H., Kaufmann, Kyle W., Hammond, Scott M., Kireev, Dmitri B., Frye, Stephen V., Pearce, Kenneth H.
Wydane w Molecules (2020)

Quantitative Characterization of Bivalent Probes for a Dual Bromodomain Protein, Transcription Initiation Factor TFIID Subunit 1

od Suh, Junghyun L., Watts, Brian, Stuckey, Jacob I., Norris-Drouin, Jacqueline L., Cholensky, Stephanie H., Dickson, Bradley M, An, Yi, Mathea, Sebastian, Salah, Eidarus, Knapp, Stefan, Khan, Abid, Adams, Alexander T., Strahl, Brian D., Sagum, Cari A., Bedford, Mark T., James, Lindsey I., Kireev, Dmitri B., Frye, Stephen V.
Wydane w Biochemistry (2018)

Discovery and Characterization of a Cellularly Potent Positive Allosteric Modulator of the Polycomb Repressive Complex 1 Chromodomain, CBX7

od Lamb, Kelsey N., Bsteh, Daniel, Dishman, Sarah N., Moussa, Hagar F., Fan, Huitao, Stuckey, Jacob I., Norris, Jacqueline L., Cholensky, Stephanie H., Li, Dongxu, Wang, Jingkui, Sagum, Cari, Stanton, Benjamin Z., Bedford, Mark T., Pearce, Kenneth H., Kenakin, Terry P., Kireev, Dmitri B., Wang, Gang Greg, James, Lindsey I., Bell, Oliver, Frye, Stephen V.
Wydane w Cell Chem Biol (2019)

A cellular chemical probe targeting the chromodomains of Polycomb Repressive Complex 1

od Stuckey, Jacob I, Dickson, Bradley M, Cheng, Nancy, Liu, Yanli, Norris, Jacqueline L, Cholensky, Stephanie H, Tempel, Wolfram, Qin, Su, Huber, Katherine G, Sagum, Cari, Black, Karynne, Li, Fengling, Huang, Xi-Ping, Roth, Bryan L, Baughman, Brandi M, Senisterra, Guillermo, Pattenden, Samantha G, Vedadi, Masoud, Brown, Peter J, Bedford, Mark T, Min, Jinrong, Arrowsmith, Cheryl H, James, Lindsey I, Frye, Stephen V
Wydane w Nat Chem Biol (2016)