Quantitative Characterization of Bivalent Probes for a Dual Bromodomain Protein, Transcription Initiation Factor TFIID Subunit 1

Multivalent binding is an efficient means to enhance the affinity and specificity of chemical probes targeting multidomain proteins in order to study their function and role in disease. While the theory of multivalent binding is straightforward, physical and structural characterization of bivalent b...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Suh, Junghyun L., Watts, Brian, Stuckey, Jacob I., Norris-Drouin, Jacqueline L., Cholensky, Stephanie H., Dickson, Bradley M, An, Yi, Mathea, Sebastian, Salah, Eidarus, Knapp, Stefan, Khan, Abid, Adams, Alexander T., Strahl, Brian D., Sagum, Cari A., Bedford, Mark T., James, Lindsey I., Kireev, Dmitri B., Frye, Stephen V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5937704/
https://ncbi.nlm.nih.gov/pubmed/29558110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00150
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados