Trypsiligase‐Catalyzed Labeling of Proteins on Living Cells

le Liebscher, Sandra, Mathea, Sebastian, Aumüller, Tobias, Pech, Andreas, Bordusa, Frank
Foilsithe in Chembiochem (2021)

A novel Hsp70 inhibitor prevents cell intoxication with the actin ADP-ribosylating Clostridium perfringens iota toxin

le Ernst, Katharina, Liebscher, Markus, Mathea, Sebastian, Granzhan, Anton, Schmid, Johannes, Popoff, Michel R., Ihmels, Heiko, Barth, Holger, Schiene-Fischer, Cordelia
Foilsithe in Sci Rep (2016)

Kinase Domain Is a Dynamic Hub for Driving LRRK2 Allostery

le Taylor, Susan S., Kaila-Sharma, Pallavi, Weng, Jui-Hung, Aoto, Phillip, Schmidt, Sven H., Knapp, Stefan, Mathea, Sebastian, Herberg, Friedrich W.
Foilsithe in Front Mol Neurosci (2020)

Sfp-Type 4′-Phosphopantetheinyl Transferase Is Indispensable for Fungal Pathogenicity

le Horbach, Ralf, Graf, Alexander, Weihmann, Fabian, Antelo, Luis, Mathea, Sebastian, Liermann, Johannes C., Opatz, Till, Thines, Eckhard, Aguirre, Jesús, Deising, Holger B.
Foilsithe 2009

Lessons from LIMK1 enzymology and their impact on inhibitor design

le Salah, Eidarus, Chatterjee, Deep, Beltrami, Alessandra, Tumber, Anthony, Preuss, Franziska, Canning, Peter, Chaikuad, Apirat, Knaus, Petra, Knapp, Stefan, Bullock, Alex N., Mathea, Sebastian
Foilsithe in Biochem J (2019)

Isoform-specific Inhibition of Cyclophilins

le Daum, Sebastian, Schumann, Michael, Mathea, Sebastian, Aumüller, Tobias, Balsley, Molly A., Constant, Stephanie L., de Lacroix, Boris Féaux, Kruska, Fabian, Braun, Manfred, Schiene-Fischer, Cordelia
Foilsithe 2009

Comprehensive Landscape of Active Deubiquitinating Enzymes Profiled by Advanced Chemoproteomics

le Pinto-Fernández, Adán, Davis, Simon, Schofield, Abigail B., Scott, Hannah C., Zhang, Ping, Salah, Eidarus, Mathea, Sebastian, Charles, Philip D., Damianou, Andreas, Bond, Gareth, Fischer, Roman, Kessler, Benedikt M.
Foilsithe in Front Chem (2019)

Conformation and dynamics of the kinase domain drive subcellular location and activation of LRRK2

le Schmidt, Sven H., Weng, Jui-Hung, Aoto, Phillip C., Boassa, Daniela, Mathea, Sebastian, Silletti, Steve, Hu, Junru, Wallbott, Maximilian, Komives, Elizabeth A., Knapp, Stefan, Herberg, Friedrich W., Taylor, Susan S.
Foilsithe in Proc Natl Acad Sci U S A (2021)

Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization

le Gebel, Jakob, Luh, Laura M, Coutandin, Daniel, Osterburg, Christian, Löhr, Frank, Schäfer, Birgit, Frombach, Ann-Sophie, Sumyk, Manuela, Buchner, Lena, Krojer, Tobias, Salah, Eidarus, Mathea, Sebastian, Güntert, Peter, Knapp, Stefan, Dötsch, Volker
Foilsithe in Cell Death Differ (2016)

Structural insights into pseudokinase domains of receptor tyrosine kinases

le Sheetz, Joshua B., Mathea, Sebastian, Karvonen, Hanna, Malhotra, Ketan, Chatterjee, Deep, Niininen, Wilhelmiina, Perttilä, Robert, Preuss, Franziska, Suresh, Krishna, Stayrook, Steven E., Tsutsui, Yuko, Radhakrishnan, Ravi, Ungureanu, Daniela, Knapp, Stefan, Lemmon, Mark A.
Foilsithe in Mol Cell (2020)

Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level

le Coutandin, Daniel, Osterburg, Christian, Srivastav, Ratnesh Kumar, Sumyk, Manuela, Kehrloesser, Sebastian, Gebel, Jakob, Tuppi, Marcel, Hannewald, Jens, Schäfer, Birgit, Salah, Eidarus, Mathea, Sebastian, Müller-Kuller, Uta, Doutch, James, Grez, Manuel, Knapp, Stefan, Dötsch, Volker
Foilsithe in eLife (2016)

Structure of the Human Protein Kinase ZAK in Complex with Vemurafenib

le Mathea, Sebastian, Abdul Azeez, Kamal R., Salah, Eidarus, Tallant, Cynthia, Wolfreys, Finn, Konietzny, Rebecca, Fischer, Roman, Lou, Hua Jane, Brennan, Paul E., Schnapp, Gisela, Pautsch, Alexander, Kessler, Benedikt M., Turk, Benjamin E., Knapp, Stefan
Foilsithe in ACS Chem Biol (2016)

Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms

le Malik, Asad U., Karapetsas, Athanasios, Nirujogi, Raja S., Mathea, Sebastian, Chatterjee, Deep, Pal, Prosenjit, Lis, Pawel, Taylor, Matthew, Purlyte, Elena, Gourlay, Robert, Dorward, Mark, Weidlich, Simone, Toth, Rachel, Polinski, Nicole K., Knapp, Stefan, Tonelli, Francesca, Alessi, Dario R.
Foilsithe in Biochem J (2021)

Quantitative Characterization of Bivalent Probes for a Dual Bromodomain Protein, Transcription Initiation Factor TFIID Subunit 1

le Suh, Junghyun L., Watts, Brian, Stuckey, Jacob I., Norris-Drouin, Jacqueline L., Cholensky, Stephanie H., Dickson, Bradley M, An, Yi, Mathea, Sebastian, Salah, Eidarus, Knapp, Stefan, Khan, Abid, Adams, Alexander T., Strahl, Brian D., Sagum, Cari A., Bedford, Mark T., James, Lindsey I., Kireev, Dmitri B., Frye, Stephen V.
Foilsithe in Biochemistry (2018)