A novel Hsp70 inhibitor prevents cell intoxication with the actin ADP-ribosylating Clostridium perfringens iota toxin

Hsp70 family proteins are folding helper proteins involved in a wide variety of cellular pathways. Members of this family interact with key factors in signal transduction, transcription, cell-cycle control, and stress response. Here, we developed the first Hsp70 low molecular weight inhibitor specif...

Full description

Saved in:
Bibliographic Details
Published in:Sci Rep
Main Authors: Ernst, Katharina, Liebscher, Markus, Mathea, Sebastian, Granzhan, Anton, Schmid, Johannes, Popoff, Michel R., Ihmels, Heiko, Barth, Holger, Schiene-Fischer, Cordelia
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738285/
https://ncbi.nlm.nih.gov/pubmed/26839186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20301
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items