Intrinsic aggregation propensity of the p63 and p73 TI domains correlates with p53R175H interaction and suggests further significance of aggregation events in the p53 family

Por Kehrloesser, Sebastian, Osterburg, Christian, Tuppi, Marcel, Schäfer, Birgit, Vousden, Karen Heather, Dötsch, Volker
Publicado no Cell Death Differ (2016)

Protein aggregation of the p63 transcription factor underlies severe skin fragility in AEC syndrome

Por Russo, Claudia, Osterburg, Christian, Sirico, Anna, Antonini, Dario, Ambrosio, Raffaele, Würz, Julia Maren, Rinnenthal, Jörg, Ferniani, Marco, Kehrloesser, Sebastian, Schäfer, Birgit, Güntert, Peter, Sinha, Satrajit, Dötsch, Volker, Missero, Caterina
Publicado no Proc Natl Acad Sci U S A (2018)

Mechanism of TAp73 inhibition by ΔNp63 and structural basis of p63/p73 hetero-tetramerization

Por Gebel, Jakob, Luh, Laura M, Coutandin, Daniel, Osterburg, Christian, Löhr, Frank, Schäfer, Birgit, Frombach, Ann-Sophie, Sumyk, Manuela, Buchner, Lena, Krojer, Tobias, Salah, Eidarus, Mathea, Sebastian, Güntert, Peter, Knapp, Stefan, Dötsch, Volker
Publicado no Cell Death Differ (2016)

Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level

Por Coutandin, Daniel, Osterburg, Christian, Srivastav, Ratnesh Kumar, Sumyk, Manuela, Kehrloesser, Sebastian, Gebel, Jakob, Tuppi, Marcel, Hannewald, Jens, Schäfer, Birgit, Salah, Eidarus, Mathea, Sebastian, Müller-Kuller, Uta, Doutch, James, Grez, Manuel, Knapp, Stefan, Dötsch, Volker
Publicado no eLife (2016)