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Chromodomain Ligand Optimization via Target-Class Directed Combinatorial Repurposing
Efforts to develop strategies for small molecule chemical probe discovery against the readers of the methyl-lysine (Kme) post-translational modification have been met with limited success. Targeted disruption of these protein-protein interactions via peptidomimetic inhibitor optimization is a promis...
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| Publicado no: | ACS Chem Biol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5026585/ https://ncbi.nlm.nih.gov/pubmed/27356154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00415 |
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