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Target class drug discovery

Selection of molecular targets based on disease understanding is a dominant paradigm in drug discovery. We argue that a focus on classes of targets with central roles in biology provides a complementary approach that has higher quality outcomes in early discovery efforts.

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書目詳細資料
發表在:Nat Chem Biol
Main Authors: Barnash, Kimberly D, James, Lindsey I, Frye, Stephen V
格式: Artigo
語言:Inglês
出版: 2017
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5973815/
https://ncbi.nlm.nih.gov/pubmed/28926557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2473
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