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Bromodomains as therapeutic targets
Acetylation of lysine residues is a post-translational modification with broad relevance to cellular signalling and disease biology. Enzymes that ‘write’ (histone acetyltransferases, HATs) and ‘erase’ (histone deacetylases, HDACs) acetylation sites are an area of extensive research in current drug d...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cambridge University Press
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3177561/ https://ncbi.nlm.nih.gov/pubmed/21933453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S1462399411001992 |
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