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Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family
Benzodiazepines are psychoactive drugs with anxiolytic, sedative, skeletal muscle relaxant and amnestic properties. Recently triazolo-benzodiazepines have been also described as potent and highly selective protein interaction inhibitors of bromodomain and extra-terminal (BET) proteins, a family of t...
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| 發表在: | Bioorg Med Chem |
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| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier Science
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4748212/ https://ncbi.nlm.nih.gov/pubmed/22137933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2011.10.080 |
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