SPOTing Acetyl-Lysine Dependent Interactions

Tekijä Picaud, Sarah, Filippakopoulos, Panagis
Julkaisussa Microarrays (Basel) (2015)

Editorial: Structural Studies of Protein Complexes in Signaling Pathways

Tekijä Prischi, Filippo, Filippakopoulos, Panagis
Julkaisussa Front Mol Biosci (2021)

SH2 domains: modulators of nonreceptor tyrosine kinase activity

Tekijä Filippakopoulos, Panagis, Müller, Susanne, Knapp, Stefan
Julkaistu 2009

Bromodomains as therapeutic targets

Tekijä Muller, Susanne, Filippakopoulos, Panagis, Knapp, Stefan
Julkaistu 2011

Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase

Tekijä Chen, Zhuoyao, Picaud, Sarah, Filippakopoulos, Panagis, D'Angiolella, Vincenzo, Bullock, Alex N.
Julkaisussa Structure (2019)

Stimulation of Hepatic Apolipoprotein A-I Production by Novel Thieno-Triazolodiazepines: Roles of the Classical Benzodiazepine Receptor, PAF Receptor, and Bromodomain Binding

Tekijä Kempen, Herman J, Bellus, Daniel, Fedorov, Oleg, Nicklisch, Silke, Filippakopoulos, Panagis, Picaud, Sarah, Knapp, Stefan
Julkaistu 2013

Extremely Tight Binding of Ruthenium Complex to Glycogen Synthase Kinase 3

Tekijä Atilla-Gokcumen, G. Ekin, Pagano, Nicholas, Streu, Craig, Maksimoska, Jasna, Filippakopoulos, Panagis, Knapp, Stefan, Meggers, Eric
Julkaistu 2008

BET Inhibition Upregulates SIRT1 and Alleviates Inflammatory Responses

Tekijä Kokkola, Tarja, Suuronen, Tiina, Pesonen, Maija, Filippakopoulos, Panagis, Salminen, Antero, Jarho, Elina M, Lahtela-Kakkonen, Maija
Julkaisussa Chembiochem (2015)

Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family

Tekijä Filippakopoulos, Panagis, Picaud, Sarah, Fedorov, Oleg, Keller, Marco, Wrobel, Matthias, Morgenstern, Olaf, Bracher, Franz, Knapp, Stefan
Julkaisussa Bioorg Med Chem (2012)

BETs inhibition attenuates oxidative stress and preserves muscle integrity in Duchenne muscular dystrophy

Tekijä Segatto, Marco, Szokoll, Roberta, Fittipaldi, Raffaella, Bottino, Cinzia, Nevi, Lorenzo, Mamchaoui, Kamel, Filippakopoulos, Panagis, Caretti, Giuseppina
Julkaisussa Nat Commun (2020)

Identification of a PGXPP degron motif in dishevelled and structural basis for its binding to the E3 ligase KLHL12

Tekijä Chen, Zhuoyao, Wasney, Gregory A., Picaud, Sarah, Filippakopoulos, Panagis, Vedadi, Masoud, D'Angiolella, Vincenzo, Bullock, Alex N.
Julkaisussa Open Biol (2020)

Crystal Structure and Inhibitor Identifications Reveal Targeting Opportunity for the Atypical MAPK Kinase ERK3

Tekijä Schröder, Martin, Filippakopoulos, Panagis, Schwalm, Martin P., Ferrer, Carla A., Drewry, David H., Knapp, Stefan, Chaikuad, Apirat
Julkaisussa Int J Mol Sci (2020)

Structure and functional characterization of the atypical human kinase haspin

Tekijä Eswaran, Jeyanthy, Patnaik, Debasis, Filippakopoulos, Panagis, Wang, Fangwei, Stein, Ross L., Murray, James W., Higgins, Jonathan M. G., Knapp, Stefan
Julkaistu 2009

Molecular Basis of Histone Tail Recognition by Human TIP5 PHD Finger and Bromodomain of the Chromatin Remodeling Complex NoRC

Tekijä Tallant, Cynthia, Valentini, Erica, Fedorov, Oleg, Overvoorde, Lois, Ferguson, Fleur M., Filippakopoulos, Panagis, Svergun, Dmitri I., Knapp, Stefan, Ciulli, Alessio
Julkaisussa Structure (2015)

MON-468 Selective Inhibition of Epigenetic Pathways Has Anti-Proliferative and Pro-Apoptotic Effects on the Mouse Corticotroph Tumor Cells, AtT20

Tekijä Lines, Kate, Stevenson, Mark, Filippakopoulos, Panagis, Muller, Susanne, Lockstone, Helen, Wright, Benjamin, Knapp, Stefan, Buck, David, Bountra, Chas, Thakker, Rajesh
Julkaisussa J Endocr Soc (2019)

Dissecting the Role of BET Bromodomain Proteins BRD2 and BRD4 in Human NK Cell Function

Tekijä Cribbs, Adam P., Filippakopoulos, Panagis, Philpott, Martin, Wells, Graham, Penn, Henry, Oerum, Henrik, Valge-Archer, Viia, Feldmann, Marc, Oppermann, Udo
Julkaisussa Front Immunol (2021)

Discovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual Screening

Tekijä Vidler, Lewis R., Filippakopoulos, Panagis, Fedorov, Oleg, Picaud, Sarah, Martin, Sarah, Tomsett, Michael, Woodward, Hannah, Brown, Nathan, Knapp, Stefan, Hoelder, Swen
Julkaistu 2013

9H-Purine Scaffold Reveals Induced-Fit Pocket Plasticity of the BRD9 Bromodomain

Tekijä Picaud, Sarah, Strocchia, Maria, Terracciano, Stefania, Lauro, Gianluigi, Mendez, Jacqui, Daniels, Danette L., Riccio, Raffaele, Bifulco, Giuseppe, Bruno, Ines, Filippakopoulos, Panagis
Julkaisussa J Med Chem (2015)

Crystal Structures of the p21-Activated Kinases PAK4, PAK5, and PAK6 Reveal Catalytic Domain Plasticity of Active Group II PAKs

Tekijä Eswaran, Jeyanthy, Lee, Wen Hwa, Debreczeni, Judit É., Filippakopoulos, Panagis, Turnbull, Andrew, Fedorov, Oleg, Deacon, Sean W., Peterson, Jeffrey R., Knapp, Stefan
Julkaistu 2007

Structures of PGAM5 Provide Insight into Active Site Plasticity and Multimeric Assembly

Tekijä Chaikuad, Apirat, Filippakopoulos, Panagis, Marcsisin, Sean R., Picaud, Sarah, Schröder, Martin, Sekine, Shiori, Ichijo, Hidenori, Engen, John R., Takeda, Kohsuke, Knapp, Stefan
Julkaisussa Structure (2017)