A Chemiluminescence-based Method for Identification of Histone Lysine Methyltransferase Inhibitors

por Quinn, Amy M, Allali-Hassani, Abdellah, Vedadi, Masoud, Simeonov, Anton
Publicado 2010

Identification of 2,4-diamino-6,7-dimethoxyquinoline derivatives as G9a inhibitors

por Srimongkolpithak, Nitipol, Sundriyal, Sandeep, Li, Fengling, Vedadi, Masoud, Fuchter, Matthew J.
Publicado en Medchemcomm (2014)

Biophysical characterization of recombinant proteins: A key to higher structural genomics success

por Vedadi, Masoud, Arrowsmith, Cheryl H., Allali-Hassani, Abdellah, Senisterra, Guillermo, Wasney, Gregory A.
Publicado 2010

Targeting human SET1/MLL family of proteins

por Vedadi, Masoud, Blazer, Levi, Eram, Mohammad S., Barsyte‐Lovejoy, Dalia, Arrowsmith, Cheryl H., Hajian, Taraneh
Publicado en Protein Sci (2017)

Identification of a PGXPP degron motif in dishevelled and structural basis for its binding to the E3 ligase KLHL12

por Chen, Zhuoyao, Wasney, Gregory A., Picaud, Sarah, Filippakopoulos, Panagis, Vedadi, Masoud, D'Angiolella, Vincenzo, Bullock, Alex N.
Publicado en Open Biol (2020)

A High-Throughput Radioactivity-Based Assay for Screening SARS-CoV-2 nsp10-nsp16 Complex

por Khalili Yazdi, Aliakbar, Li, Fengling, Devkota, Kanchan, Perveen, Sumera, Ghiabi, Pegah, Hajian, Taraneh, Bolotokova, Albina, Vedadi, Masoud
Publicado en SLAS Discov (2021)

PR Domain-containing Protein 7 (PRDM7) Is a Histone 3 Lysine 4 Trimethyltransferase

por Blazer, Levi L., Lima-Fernandes, Evelyne, Gibson, Elisa, Eram, Mohammad S., Loppnau, Peter, Arrowsmith, Cheryl H., Schapira, Matthieu, Vedadi, Masoud
Publicado en J Biol Chem (2016)

A High-Throughput RNA Displacement Assay for Screening SARS-CoV-2 nsp10-nsp16 Complex toward Developing Therapeutics for COVID-19

por Perveen, Sumera, Khalili Yazdi, Aliakbar, Devkota, Kanchan, Li, Fengling, Ghiabi, Pegah, Hajian, Taraneh, Loppnau, Peter, Bolotokova, Albina, Vedadi, Masoud
Publicado en SLAS Discov (2021)

Structural basis for molecular recognition and presentation of histone H3 By WDR5

por Schuetz, Anja, Allali-Hassani, Abdellah, Martín, Fernando, Loppnau, Peter, Vedadi, Masoud, Bochkarev, Alexey, Plotnikov, Alexander N, Arrowsmith, Cheryl H, Min, Jinrong
Publicado 2006

Crystal Structures of Human Choline Kinase Isoforms in Complex with Hemicholinium-3: SINGLE AMINO ACID NEAR THE ACTIVE SITE INFLUENCES INHIBITOR SENSITIVITY

por Hong, Bum Soo, Allali-Hassani, Abdellah, Tempel, Wolfram, Finerty, Patrick J., MacKenzie, Farrell, Dimov, Svetoslav, Vedadi, Masoud, Park, Hee-Won
Publicado 2010

Discovery of Bisubstrate Inhibitors of Nicotinamide N-Methyltransferase (NNMT)

por Babault, Nicolas, Allali-Hassani, Abdellah, Li, Fengling, Fan, Jie, Yue, Alex, Ju, Kevin, Liu, Feng, Vedadi, Masoud, Liu, Jing, Jin, Jian
Publicado en J Med Chem (2018)

Structural Studies of a Four-MBT Repeat Protein MBTD1

por Eryilmaz, Jitka, Pan, Patricia, Amaya, Maria F., Allali-Hassani, Abdellah, Dong, Aiping, Adams-Cioaba, Melanie A., MacKenzie, Farrell, Vedadi, Masoud, Min, Jinrong
Publicado 2009

Structural Studies of the Tandem Tudor Domains of Fragile X Mental Retardation Related Proteins FXR1 and FXR2

por Adams-Cioaba, Melanie A., Guo, Yahong, Bian, ChuanBing, Amaya, Maria F., Lam, Robert, Wasney, Gregory A., Vedadi, Masoud, Xu, Chao, Min, Jinrong
Publicado 2010

Characterization of 14-3-3 Proteins from Cryptosporidium parvum

por Brokx, Stephen J., Wernimont, Amy K., Dong, Aiping, Wasney, Gregory A., Lin, Yu-Hui, Lew, Jocelyne, Vedadi, Masoud, Lee, Wen Hwa, Hui, Raymond
Publicado 2011

A chemical tool for chemiprecipitation of the lysine methyltransferase, G9a, in vitro and in vivo

por Konze, Kyle D., Pattenden, Samantha G., Liu, Feng, Barsyte-Lovejoy, Dalia, Li, Fengling, Simon, Jeremy M., Davis, Ian J., Vedadi, Masoud, Jin, Jian
Publicado 2014

Design of a Fluorescent Ligand Targeting the S-adenosylmethioine Binding Site of the Histone Methyltransferase MLL1

por Luan, Yepeng, Blazer, Levi L., Hu, Hao, Hajian, Taraneh, Zhang, Jing, Wu, Hong, Houliston, Scott, Arrowsmith, Cheryl H., Vedadi, Masoud, Zheng, Yujun George
Publicado en Org Biomol Chem (2016)

Discovery of a Dual PRMT5–PRMT7 Inhibitor

por Smil, David, Eram, Mohammad S., Li, Fengling, Kennedy, Steven, Szewczyk, Magdalena M., Brown, Peter J., Barsyte-Lovejoy, Dalia, Arrowsmith, Cheryl H., Vedadi, Masoud, Schapira, Matthieu
Publicado en ACS Med Chem Lett (2015)

Structural basis of arginine asymmetrical dimethylation by PRMT6

por Wu, Hong, Zheng, Weihong, Eram, Mohammad S., Vhuiyan, Mynol, Dong, Aiping, Zeng, Hong, He, Hao, Brown, Peter, Frankel, Adam, Vedadi, Masoud, Luo, Minkui, Min, Jinrong
Publicado en Biochem J (2016)

Crystal structure and activity-based labeling reveal the mechanisms for linkage-specific substrate recognition by deubiquitinase USP9X

por Paudel, Prajwal, Zhang, Qi, Leung, Charles, Greenberg, Harrison C., Guo, Yusong, Chern, Yi-Hsuan, Dong, Aiping, Li, Yanjun, Vedadi, Masoud, Zhuang, Zhihao, Tong, Yufeng
Publicado en Proc Natl Acad Sci U S A (2019)

Human MettL3–MettL14 complex is a sequence-specific DNA adenine methyltransferase active on single-strand and unpaired DNA in vitro

por Woodcock, Clayton B., Yu, Dan, Hajian, Taraneh, Li, Jia, Huang, Yun, Dai, Nan, Corrêa, Ivan R., Wu, Tao, Vedadi, Masoud, Zhang, Xing, Cheng, Xiaodong
Publicado en Cell Discov (2019)