Structural Studies of the Tandem Tudor Domains of Fragile X Mental Retardation Related Proteins FXR1 and FXR2

BACKGROUND: Expansion of the CGG trinucleotide repeat in the 5′-untranslated region of the FMR1, fragile X mental retardation 1, gene results in suppression of protein expression for this gene and is the underlying cause of Fragile X syndrome. In unaffected individuals, the FMRP protein, together wi...

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Autores principales: Adams-Cioaba, Melanie A., Guo, Yahong, Bian, ChuanBing, Amaya, Maria F., Lam, Robert, Wasney, Gregory A., Vedadi, Masoud, Xu, Chao, Min, Jinrong
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970552/
https://ncbi.nlm.nih.gov/pubmed/21072162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013559
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