Gene length matters in neurons

Por Zylka, Mark J., Simon, Jeremy M., Philpot, Benjamin D.
Publicado no Neuron (2015)

Using FAIRE (Formaldehyde-Assisted Isolation of Regulatory Elements) to isolate active regulatory DNA

Por Simon, Jeremy M., Giresi, Paul G., Davis, Ian J., Lieb, Jason D.
Publicado em 2012

Widespread chromatin accessibility at repetitive elements links stem cells with human cancer

Por Gomez, Nicholas C., Hepperla, Austin, Dumitru, Raluca, Simon, Jeremy M., Fang, Fang, Davis, Ian J.
Publicado no Cell Rep (2016)

Identification of chemicals that mimic transcriptional changes associated with autism, brain aging and neurodegeneration

Por Pearson, Brandon L., Simon, Jeremy M., McCoy, Eric S., Salazar, Gabriela, Fragola, Giulia, Zylka, Mark J.
Publicado no Nat Commun (2016)

The Open Chromatin Landscape of Kaposi's Sarcoma-Associated Herpesvirus

Por Hilton, Isaac B., Simon, Jeremy M., Lieb, Jason D., Davis, Ian J., Damania, Blossom, Dittmer, Dirk P.
Publicado em 2013

Enhanced Nociception in Angelman Syndrome Model Mice

Por McCoy, Eric S., Taylor-Blake, Bonnie, Aita, Megumi, Simon, Jeremy M., Philpot, Benjamin D., Zylka, Mark J.
Publicado no J Neurosci (2017)

Topoisomerase 1 Regulates Gene Expression in Neurons through Cleavage Complex-Dependent and -Independent Mechanisms

Por Mabb, Angela M., Simon, Jeremy M., King, Ian F., Lee, Hyeong-Min, An, Lin-Kun, Philpot, Benjamin D., Zylka, Mark J.
Publicado no PLoS One (2016)

Tumor-specific retargeting of an oncogenic transcription factor chimera results in dysregulation of chromatin and transcription

Por Patel, Mukund, Simon, Jeremy M., Iglesia, Michael D., Wu, Sam B., McFadden, Andrew W., Lieb, Jason D., Davis, Ian J.
Publicado em 2012

A chemical tool for chemiprecipitation of the lysine methyltransferase, G9a, in vitro and in vivo

Por Konze, Kyle D., Pattenden, Samantha G., Liu, Feng, Barsyte-Lovejoy, Dalia, Li, Fengling, Simon, Jeremy M., Davis, Ian J., Vedadi, Masoud, Jin, Jian
Publicado em 2014

Loss of Arp2/3 induces an NF-κB–dependent, nonautonomous effect on chemotactic signaling

Por Wu, Congying, Haynes, Elizabeth M., Asokan, Sreeja B., Simon, Jeremy M., Sharpless, Norman E., Baldwin, Albert S., Davis, Ian J., Johnson, Gary L., Bear, James E.
Publicado em 2013

A Role for Widely Interspaced Zinc Finger (WIZ) in Retention of the G9a Methyltransferase on Chromatin

Por Simon, Jeremy M., Parker, Joel S., Liu, Feng, Rothbart, Scott B., Ait-Si-Ali, Slimane, Strahl, Brian D., Jin, Jian, Davis, Ian J., Mosley, Amber L., Pattenden, Samantha G.
Publicado no J Biol Chem (2015)

Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide

Por Schmid, Ralf S., Simon, Jeremy M., Vitucci, Mark, McNeill, Robert S., Bash, Ryan E., Werneke, Andrea M., Huey, Lauren, White, Kristen K., Ewend, Matthew G., Wu, Jing, Miller, C. Ryan
Publicado no Neuro Oncol (2016)

PTEN deficiency mediates a reciprocal response to IGF-1 and mTOR inhibition

Por Patel, Mukund, Gomez, Nicholas C., McFadden, Andrew W., Moats-Staats, Billie M., Wu, Sam, Rojas, Andres, Sapp, Travis, Simon, Jeremy M., Smith, Scott V., Kaiser-Rogers, Kathleen, Davis, Ian J.
Publicado no Mol Cancer Res (2014)

High-throughput small molecule screen identifies inhibitors of aberrant chromatin accessibility

Por Pattenden, Samantha G., Simon, Jeremy M., Wali, Aminah, Jayakody, Chatura N., Troutman, Jacob, McFadden, Andrew W., Wooten, Joshua, Wood, Cameron C., Frye, Stephen V., Janzen, William P., Davis, Ian J.
Publicado no Proc Natl Acad Sci U S A (2016)

LKB1 loss in melanoma disrupts directional migration toward extracellular matrix cues

Por Chan, Keefe T., Asokan, Sreeja B., King, Samantha J., Bo, Tao, Dubose, Evan S., Liu, Wenjin, Berginski, Matthew E., Simon, Jeremy M., Davis, Ian J., Gomez, Shawn M., Sharpless, Norman E., Bear, James E.
Publicado em 2014

An oncogenic Ezh2 mutation cooperates with particular genetic alterations to induce tumors in mice and redistributes H3K27 trimethylation throughout the genome

Por Souroullas, George P., Jeck, William R., Parker, Joel S., Simon, Jeremy M., Liu, Jie-Yu, Paulk, Joshiawa, Xiong, Jessie, Clark, Kelly S., Fedoriw, Yuri, Qi, Jun, Burd, Christin E., Bradner, James E., Sharpless, Norman E.
Publicado no Nat Med (2016)

Genomic profiles of low-grade murine gliomas evolve during progression to glioblastoma

Por Vitucci, Mark, Irvin, David M, McNeill, Robert S, Schmid, Ralf S, Simon, Jeremy M, Dhruv, Harshil D, Siegel, Marni B, Werneke, Andrea M, Bash, Ryan E, Kim, Seungchan, Berens, Michael E, Miller, C Ryan
Publicado no Neuro Oncol (2017)

A map of open chromatin in human pancreatic islets

Por Gaulton, Kyle J., Nammo, Takao, Pasquali, Lorenzo, Simon, Jeremy M., Giresi, Paul G., Fogarty, Marie P., Panhuis, Tami M., Mieczkowski, Piotr, Secchi, Antonio, Bosco, Domenico, Berney, Thierry, Montanya, Eduard, Mohlke, Karen L., Lieb, Jason D., Ferrer, Jorge
Publicado em 2010

Variation in chromatin accessibility in human kidney cancer links H3K36 methyltransferase loss with widespread RNA processing defects

Por Simon, Jeremy M., Hacker, Kathryn E., Singh, Darshan, Brannon, A. Rose, Parker, Joel S., Weiser, Matthew, Ho, Thai H., Kuan, Pei-Fen, Jonasch, Eric, Furey, Terrence S., Prins, Jan F., Lieb, Jason D., Rathmell, W. Kimryn, Davis, Ian J.
Publicado em 2014

Molecular classification of Crohn’s disease reveals two clinically relevant subtypes

Por Weiser, Matthew, Simon, Jeremy M., Kochar, Bharati, Tovar, Adelaide, Israel, Jennifer W., Robinson, Adam, Gipson, Gregory R., Schaner, Matthew S., Herfarth, Hans H., Sartor, R. Balfour, McGovern, Dermot P.B., Rahbar, Reza, Sadiq, Timothy S., Koruda, Mark J., Furey, Terrence S., Sheikh, Shehzad Z.
Publicado no Gut (2016)