PTEN deficiency mediates a reciprocal response to IGF-1 and mTOR inhibition

Recent evidence implicates the insulin-like growth factor (IGF) pathway in development of Ewing Sarcoma, a highly malignant bone and soft tissue tumor that primarily affects children and young adults. Despite promising results from preclinical studies of therapies that target this pathway, early pha...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Mol Cancer Res
Main Authors: Patel, Mukund, Gomez, Nicholas C., McFadden, Andrew W., Moats-Staats, Billie M., Wu, Sam, Rojas, Andres, Sapp, Travis, Simon, Jeremy M., Smith, Scott V., Kaiser-Rogers, Kathleen, Davis, Ian J.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4233155/
https://ncbi.nlm.nih.gov/pubmed/24994750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-14-0006
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker