Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) promotes glioblastoma cell chemotaxis via Lyn activation

Por Dhruv, Harshil D., Whitsett, Timothy G., Jameson, Nathan M., Patel, Falak, Winkles, Jeffrey A., Berens, Michael E., Tran, Nhan L.
Publicado em 2014

Propentofylline inhibits glioblastoma cell invasion and survival by targeting the TROY signaling pathway

Por Dhruv, Harshil D., Roos, Alison, Tomboc, Patrick J, Tuncali, Serdar, Chavez, Ashley, Matthews, Ian, Berens, Michael E., Loftus, Joseph C, Tran, Nhan L.
Publicado no J Neurooncol (2015)

Reciprocal Activation of Transcription Factors Underlies the Dichotomy between Proliferation and Invasion of Glioma Cells

Por Dhruv, Harshil D., McDonough Winslow, Wendy S., Armstrong, Brock, Tuncali, Serdar, Eschbacher, Jenny, Kislin, Kerri, Loftus, Joseph C., Tran, Nhan L., Berens, Michael E.
Publicado em 2013

Molecular determinants of lung cancer metastasis to the central nervous system

Por Whitsett, Timothy G., Inge, Landon J., Dhruv, Harshil D., Cheung, Philip Y., Weiss, Glen J., Bremner, Ross M., Winkles, Jeffrey A., Tran, Nhan L.
Publicado no Transl Lung Cancer Res (2013)

SGEF is Regulated via TWEAK/Fn14/NF-κB Signaling and Promotes Survival by Modulation of the DNA Repair Response to Temozolomide

Por Fortin Ensign, Shannon P., Roos, Alison, Mathews, Ian T., Dhruv, Harshil D., Tuncali, Serdar, Sarkaria, Jann N., Symons, Marc H., Loftus, Joseph C., Berens, Michael E., Tran, Nhan L.
Publicado no Mol Cancer Res (2016)

EGFRvIII-Stat5 Signaling Enhances Glioblastoma Cell Migration and Survival

Por Roos, Alison, Dhruv, Harshil D., Peng, Sen, Inge, Landon J., Tuncali, Serdar, Pineda, Michael, Millard, Nghia, Mayo, Zachary, Eschbacher, Jennifer M., Loftus, Joseph C., Winkles, Jeffrey A., Tran, Nhan L.
Publicado no Mol Cancer Res (2018)

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

Por Hangauer, Matthew J., Viswanathan, Vasanthi S., Ryan, Matthew J., Bole, Dhruv, Eaton, John K., Matov, Alexandre, Galeas, Jacqueline, Dhruv, Harshil D., Berens, Michael E., Schreiber, Stuart L., McCormick, Frank, McManus, Michael T.
Publicado no Nature (2017)

Genomic profiles of low-grade murine gliomas evolve during progression to glioblastoma

Por Vitucci, Mark, Irvin, David M, McNeill, Robert S, Schmid, Ralf S, Simon, Jeremy M, Dhruv, Harshil D, Siegel, Marni B, Werneke, Andrea M, Bash, Ryan E, Kim, Seungchan, Berens, Michael E, Miller, C Ryan
Publicado no Neuro Oncol (2017)

Identification of aurintricarboxylic acid as a selective inhibitor of the TWEAK-Fn14 signaling pathway in glioblastoma cells

Por Roos, Alison, Dhruv, Harshil D., Mathews, Ian T., Inge, Landon J., Tuncali, Serdar, Hartman, Lauren K., Chow, Donald, Millard, Nghia, Yin, Holly H., Kloss, Jean, Loftus, Joseph C., Winkles, Jeffrey A., Berens, Michael E., Tran, Nhan L.
Publicado no Oncotarget (2017)

Evaluation of pre-analytical factors affecting plasma DNA analysis

Por Markus, Havell, Contente-Cuomo, Tania, Farooq, Maria, Liang, Winnie S., Borad, Mitesh J., Sivakumar, Shivan, Gollins, Simon, Tran, Nhan L., Dhruv, Harshil D., Berens, Michael E., Bryce, Alan, Sekulic, Aleksandar, Ribas, Antoni, Trent, Jeffrey M., LoRusso, Patricia M., Murtaza, Muhammed
Publicado no Sci Rep (2018)

Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy Is Regulated by MNK1 and mRNA Translation

Por Bell, Jonathan B., Eckerdt, Frank, Dhruv, Harshil D., Finlay, Darren, Peng, Sen, Kim, Seungchan, Kroczynska, Barbara, Beauchamp, Elspeth M., Alley, Kristen, Clymer, Jessica, Goldman, Stewart, Cheng, Shi-Yuan, James, C. David, Nakano, Ichiro, Horbinski, Craig, Mazar, Andrew P., Vuori, Kristiina, Kumthekar, Priya, Raizer, Jeffrey, Berens, Michael E., Platanias, Leonidas C.
Publicado no Mol Cancer Res (2017)

Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma

Por McNeill, Robert S, Canoutas, Demitra A, Stuhlmiller, Timothy J, Dhruv, Harshil D, Irvin, David M, Bash, Ryan E, Angus, Steven P, Herring, Laura E, Simon, Jeremy M, Skinner, Kasey R, Limas, Juanita C, Chen, Xin, Schmid, Ralf S, Siegel, Marni B, Van Swearingen, Amanda E D, Hadler, Michael J, Sulman, Erik P, Sarkaria, Jann N, Anders, Carey K, Graves, Lee M, Berens, Michael E, Johnson, Gary L, Miller, C Ryan
Publicado no Neuro Oncol (2017)