Genomic profiles of low-grade murine gliomas evolve during progression to glioblastoma

BACKGROUND: Gliomas are diverse neoplasms with multiple molecular subtypes. How tumor-initiating mutations relate to molecular subtypes as these tumors evolve during malignant progression remains unclear. METHODS: We used genetically engineered mouse models, histopathology, genetic lineage tracing,...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Vitucci, Mark, Irvin, David M, McNeill, Robert S, Schmid, Ralf S, Simon, Jeremy M, Dhruv, Harshil D, Siegel, Marni B, Werneke, Andrea M, Bash, Ryan E, Kim, Seungchan, Berens, Michael E, Miller, C Ryan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570221/
https://ncbi.nlm.nih.gov/pubmed/28398584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox050
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