A Role for Widely Interspaced Zinc Finger (WIZ) in Retention of the G9a Methyltransferase on Chromatin

G9a and GLP lysine methyltransferases form a heterodimeric complex that is responsible for the majority of histone H3 lysine 9 mono- and di-methylation (H3K9me1/me2). Widely interspaced zinc finger (WIZ) associates with the G9a-GLP protein complex, but its role in mediating lysine methylation is poo...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Simon, Jeremy M., Parker, Joel S., Liu, Feng, Rothbart, Scott B., Ait-Si-Ali, Slimane, Strahl, Brian D., Jin, Jian, Davis, Ian J., Mosley, Amber L., Pattenden, Samantha G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Gene Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646261/
https://ncbi.nlm.nih.gov/pubmed/26338712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.654459
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