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The zinc finger proteins ZNF644 and WIZ regulate the G9a/GLP complex for gene repression

The G9a/GLP complex mediates mono- and dimethylation of Lys9 of histone H3 at specific gene loci, which is associated with transcriptional repression. However, the molecular mechanism by which the G9a/GLP complex is targeted to the specific gene loci for H3K9 methylation is unclear. In this study, w...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Bian, Chunjing, Chen, Qiang, Yu, Xiaochun
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365668/
https://ncbi.nlm.nih.gov/pubmed/25789554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05606
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