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A Chemiluminescence-based Method for Identification of Histone Lysine Methyltransferase Inhibitors
Methylation of lysine residues, catalyzed by histone methyltransferase (HMT) enzymes, is one of many modifications of core histone proteins that regulate transcription and chromatin structure. G9a is the predominant HMT in mammalian euchromatin and recent data suggest that it is required to perpetua...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891548/ https://ncbi.nlm.nih.gov/pubmed/20567762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b921912a |
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