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A Chemiluminescence-based Method for Identification of Histone Lysine Methyltransferase Inhibitors

Methylation of lysine residues, catalyzed by histone methyltransferase (HMT) enzymes, is one of many modifications of core histone proteins that regulate transcription and chromatin structure. G9a is the predominant HMT in mammalian euchromatin and recent data suggest that it is required to perpetua...

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Bibliografiska uppgifter
Huvudupphovsmän: Quinn, Amy M, Allali-Hassani, Abdellah, Vedadi, Masoud, Simeonov, Anton
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891548/
https://ncbi.nlm.nih.gov/pubmed/20567762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b921912a
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