ADDING A LYSINE MIMIC IN THE DESIGN OF POTENT INHIBITORS OF HISTONE LYSINE METHYLTRANSFERASES

Dynamic histone lysine methylation involves the activities of modifying enzymes (writers), enzymes removing modifications (erasers) and readers of the histone code. One common feature of these activities is the recognition of lysines in methylated and unmethylated states, whether they are substrates...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chang, Yanqi, Ganesh, Thota, Horton, John R., Spannhoff, Astrid, Liu, Jin, Sun, Aiming, Zhang, Xing, Bedford, Mark T., Shinkai, Yoichi, Snyder, James P., Cheng, Xiaodong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895764/
https://ncbi.nlm.nih.gov/pubmed/20434463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.04.048
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