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Protein lysine methyltransferase G9a acts on non-histone targets
By methylation of peptide arrays, we determined the specificity profile of the protein methyltransferase G9a. We show that it mostly recognizes an Arg-Lys sequence and that its activity is inhibited by methylation of the arginine residue. Using the specificity profile, we identified new non-histone...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2696268/ https://ncbi.nlm.nih.gov/pubmed/18438403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.88 |
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