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Continuous enzymatic assay for histone lysine methyltransferases

We describe a continuous peptide methylation assay using the Neurospora crassa Dim-5 histone H3 lysine 9 (H3K9) methyltransferase as a model system. The assay uses streptavidin FlashPlates coated with target peptide. Since no washing and pipeting steps were required after the addition of the enzyme/...

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Detalhes bibliográficos
Main Authors: Rathert, Philipp, Cheng, Xiaodong, Jeltsch, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703000/
https://ncbi.nlm.nih.gov/pubmed/18072589
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