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A Chemiluminescence-based Method for Identification of Histone Lysine Methyltransferase Inhibitors

Methylation of lysine residues, catalyzed by histone methyltransferase (HMT) enzymes, is one of many modifications of core histone proteins that regulate transcription and chromatin structure. G9a is the predominant HMT in mammalian euchromatin and recent data suggest that it is required to perpetua...

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Main Authors: Quinn, Amy M, Allali-Hassani, Abdellah, Vedadi, Masoud, Simeonov, Anton
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891548/
https://ncbi.nlm.nih.gov/pubmed/20567762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b921912a
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