Sinefungin Derivatives as Inhibitors and Structure Probes of Protein Lysine Methyltransferase SETD2

Epigenetic regulations are involved in numerous physiological and pathogenic processes. Among the key regulators that orchestrate epigenetic signaling are over 50 human protein lysine methyltransferases (PKMTs). Interrogating the functions of individual PKMTs can be facilitated by target-specific PK...

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Hoofdauteurs: Zheng, Weihong, Ibáñez, Glorymar, Wu, Hong, Blum, Gil, Zeng, Hong, Dong, Aiping, Li, Fengling, Hajian, Taraneh, Allali-Hassani, Abdellah, Amaya, Maria F., Siarheyeva, Alena, Yu, Wenyu, Brown, Peter J., Schapira, Matthieu, Vedadi, Masoud, Min, Jinrong, Luo, Minkui
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504124/
https://ncbi.nlm.nih.gov/pubmed/23043551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja307060p
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