Sinefungin Derivatives as Inhibitors and Structure Probes of Protein Lysine Methyltransferase SETD2

Epigenetic regulations are involved in numerous physiological and pathogenic processes. Among the key regulators that orchestrate epigenetic signaling are over 50 human protein lysine methyltransferases (PKMTs). Interrogating the functions of individual PKMTs can be facilitated by target-specific PK...

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主要な著者: Zheng, Weihong, Ibáñez, Glorymar, Wu, Hong, Blum, Gil, Zeng, Hong, Dong, Aiping, Li, Fengling, Hajian, Taraneh, Allali-Hassani, Abdellah, Amaya, Maria F., Siarheyeva, Alena, Yu, Wenyu, Brown, Peter J., Schapira, Matthieu, Vedadi, Masoud, Min, Jinrong, Luo, Minkui
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504124/
https://ncbi.nlm.nih.gov/pubmed/23043551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja307060p
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