Sinefungin Derivatives as Inhibitors and Structure Probes of Protein Lysine Methyltransferase SETD2

Epigenetic regulations are involved in numerous physiological and pathogenic processes. Among the key regulators that orchestrate epigenetic signaling are over 50 human protein lysine methyltransferases (PKMTs). Interrogating the functions of individual PKMTs can be facilitated by target-specific PK...

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Hauptverfasser: Zheng, Weihong, Ibáñez, Glorymar, Wu, Hong, Blum, Gil, Zeng, Hong, Dong, Aiping, Li, Fengling, Hajian, Taraneh, Allali-Hassani, Abdellah, Amaya, Maria F., Siarheyeva, Alena, Yu, Wenyu, Brown, Peter J., Schapira, Matthieu, Vedadi, Masoud, Min, Jinrong, Luo, Minkui
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504124/
https://ncbi.nlm.nih.gov/pubmed/23043551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja307060p
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