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Trimethylation of Histone H3 Lysine 36 by Human Methyltransferase PRDM9 Protein
PRDM9 (PR domain-containing protein 9) is a meiosis-specific protein that trimethylates H3K4 and controls the activation of recombination hot spots. It is an essential enzyme in the progression of early meiotic prophase. Disruption of the PRDM9 gene results in sterility in mice. In human, several PR...
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| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2014
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4002121/ https://ncbi.nlm.nih.gov/pubmed/24634223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.523183 |
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