Trimethylation of Histone H3 Lysine 36 by Human Methyltransferase PRDM9 Protein

PRDM9 (PR domain-containing protein 9) is a meiosis-specific protein that trimethylates H3K4 and controls the activation of recombination hot spots. It is an essential enzyme in the progression of early meiotic prophase. Disruption of the PRDM9 gene results in sterility in mice. In human, several PR...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Eram, Mohammad S., Bustos, Susan P., Lima-Fernandes, Evelyne, Siarheyeva, Alena, Senisterra, Guillermo, Hajian, Taraneh, Chau, Irene, Duan, Shili, Wu, Hong, Dombrovski, Ludmila, Schapira, Matthieu, Arrowsmith, Cheryl H., Vedadi, Masoud
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2014
Aiheet:
Enzymology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002121/
https://ncbi.nlm.nih.gov/pubmed/24634223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.523183
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