Meteorological Disasters in Medieval Britain (AD 1000‒1500)

Por Brown, Peter J.
Publicado no Historical Catastrophe Studies / Historische Katastrophenforschung (2023)

Open access chemical probes for epigenetic targets

Por Brown, Peter J, Müller, Susanne
Publicado no Future Med Chem (2015)

How anthropological theory and methods can advance global mental health

Por Kohrt, Brandon A, Mendenhall, Emily, Brown, Peter J
Publicado no Lancet Psychiatry (2016)

Structure-activity relationship studies of SETD8 inhibitors

Por Ma, Anqi, Yu, Wenyu, Xiong, Yan, Butler, Kyle V., Brown, Peter J., Jin, Jian
Publicado no Medchemcomm (2014)

Accessing Protein Methyltransferase and Demethylase Enzymology Using Microfluidic Capillary Electrophoresis

Por Wigle, Tim J., Provencher, Laurel M., Norris, Jacqueline L., Jin, Jian, Brown, Peter J., Frye, Stephen V., Janzen, William P.
Publicado em 2010

Freshwater fluxes in the Weddell Gyre: results from δ(18)O

Por Brown, Peter J., Meredith, Michael P., Jullion, Loïc, Naveira Garabato, Alberto, Torres-Valdés, Sinhue, Holland, Paul, Leng, Melanie J., Venables, Hugh
Publicado em 2014

Discovery of a Dual PRMT5–PRMT7 Inhibitor

Por Smil, David, Eram, Mohammad S., Li, Fengling, Kennedy, Steven, Szewczyk, Magdalena M., Brown, Peter J., Barsyte-Lovejoy, Dalia, Arrowsmith, Cheryl H., Vedadi, Masoud, Schapira, Matthieu
Publicado no ACS Med Chem Lett (2015)

Structure of the Catalytic Domain of EZH2 Reveals Conformational Plasticity in Cofactor and Substrate Binding Sites and Explains Oncogenic Mutations

Por Wu, Hong, Zeng, Hong, Dong, Aiping, Li, Fengling, He, Hao, Senisterra, Guillermo, Seitova, Alma, Duan, Shili, Brown, Peter J., Vedadi, Masoud, Arrowsmith, Cheryl H., Schapira, Matthieu
Publicado em 2013

SET9-Mediated Regulation of TGF-β Signaling Links Protein Methylation to Pulmonary Fibrosis

Por Elkouris, Maximilianos, Kontaki, Haroula, Stavropoulos, Athanasios, Antonoglou, Anastasia, Nikolaou, Kostas C., Samiotaki, Martina, Szantai, Eszter, Saviolaki, Dimitra, Brown, Peter J., Sideras, Paschalis, Panayotou, George, Talianidis, Iannis
Publicado no Cell Rep (2016)

Discovery of Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase

Por Xiong, Yan, Li, Fengling, Babault, Nicolas, Dong, Aiping, Zeng, Hong, Wu, Hong, Chen, Xin, Arrowsmith, Cheryl H., Brown, Peter J., Liu, Jing, Vedadi, Masoud, Jin, Jian
Publicado no J Med Chem (2017)

Structure–Activity Relationship Studies for Enhancer of Zeste Homologue 2 (EZH2) and Enhancer of Zeste Homologue 1 (EZH1) Inhibitors

Por Yang, Xiaobao, Li, Fengling, Konze, Kyle D., Meslamani, Jamel, Ma, Anqi, Brown, Peter J., Zhou, Ming-Ming, Arrowsmith, Cheryl H., Kaniskan, H. Ümit, Vedadi, Masoud, Jin, Jian
Publicado no J Med Chem (2016)

Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ

Por Kliewer, Steven A., Sundseth, Scott S., Jones, Stacey A., Brown, Peter J., Wisely, G. Bruce, Koble, Cecilia S., Devchand, Pallavi, Wahli, Walter, Willson, Timothy M., Lenhard, James M., Lehmann, Jürgen M.
Publicado em 1997

Identification of Novel Functionally Selective κ-Opioid Receptor Scaffolds

Por White, Kate L., Scopton, Alex P., Rives, Marie-Laure, Bikbulatov, Ruslan V., Polepally, Prabhakar R., Brown, Peter J., Kenakin, Terrance, Javitch, Jonathan A., Zjawiony, Jordan K., Roth, Bryan L.
Publicado em 2014

Bromo-deaza-SAH: a potent and selective DOT1L inhibitor

Por Yu, Wenyu, Smil, David, Li, Fengling, Tempel, Wolfram, Fedorov, Oleg, Nguyen, Kong T., Bolshan, Yuri, Al-Awar, Rima, Knapp, Stefan, Arrowsmith, Cheryl H., Vedadi, Masoud, Brown, Peter J., Schapira, Matthieu
Publicado no Bioorg Med Chem (2013)

Genome-wide profiling of histone H3 lysine 27 and lysine 4 trimethylation in multiple myeloma reveals the importance of Polycomb gene targeting and highlights EZH2 as a potential t...

Por Agarwal, Prasoon, Alzrigat, Mohammad, Párraga, Alba Atienza, Enroth, Stefan, Singh, Umashankar, Ungerstedt, Johanna, Österborg, Anders, Brown, Peter J., Ma, Anqi, Jin, Jian, Nilsson, Kenneth, Öberg, Fredrik, Kalushkova, Antonia, Jernberg-Wiklund, Helena
Publicado no Oncotarget (2016)

Structure Based Design of a Covalent Inhibitor of the SET Domain-Containing Protein 8 (SETD8) Lysine Methyltransferase

Por Butler, Kyle V., Ma, Anqi, Yu, Wenyu, Li, Fengling, Tempel, Wolfram, Babault, Nicolas, Pittella-Silva, Fabio, Shao, Jason, Wang, Junyi, Luo, Minkui, Vedadi, Masoud, Brown, Peter J., Arrowsmith, Cheryl H., Jin, Jian
Publicado no J Med Chem (2016)

Optimization of Cellular Activity of G9a Inhibitors 7-Aminoalkoxy-quinazolines

Por Liu, Feng, Barsyte-Lovejoy, Dalia, Allali-Hassani, Abdellah, He, Yunlong, Herold, J. Martin, Chen, Xin, Yates, Christopher M., Frye, Stephen V., Brown, Peter J., Huang, Jing, Vedadi, Masoud, Arrowsmith, Cheryl H., Jin, Jian
Publicado em 2011

Discovery and Development of Potent and Selective Inhibitors of Histone Methyltransferase G9a

Por Sweis, Ramzi F., Pliushchev, Marina, Brown, Peter J., Guo, Jun, Li, Fengling, Maag, David, Petros, Andrew M., Soni, Nirupama B., Tse, Chris, Vedadi, Masoud, Michaelides, Michael R., Chiang, Gary G., Pappano, William N.
Publicado em 2014

Exploiting an Allosteric Binding Site of PRMT3 Yields Potent and Selective Inhibitors

Por Liu, Feng, Li, Fengling, Ma, Anqi, Dobrovetsky, Elena, Dong, Aiping, Gao, Cen, Korboukh, Ilia, Liu, Jing, Smil, David, Brown, Peter J., Frye, Stephen V., Arrowsmith, Cheryl H., Schapira, Matthieu, Vedadi, Masoud, Jin, Jian
Publicado no J Med Chem (2013)

Discovery of Peptidomimetic Ligands of EED as Allosteric Inhibitors of PRC2

Por Barnash, Kimberly D., The, Juliana, Norris-Drouin, Jacqueline L., Cholensky, Stephanie H., Worley, Beau M., Li, Fengling, Stuckey, Jacob I., Brown, Peter J., Vedadi, Masoud, Arrowsmith, Cheryl H., Frye, Stephen V., James, Lindsey I.
Publicado no ACS Comb Sci (2017)