Structural basis of arginine asymmetrical dimethylation by PRMT6

PRMT6 is a type I protein arginine methyltransferase, generating the asymmetric dimethylarginine mark on proteins such as histone H3R2. Asymmetric dimethylation of histone H3R2 by PRMT6 acts as a repressive mark that antagonizes trimethylation of H3 lysine 4 by the MLL histone H3K4 methyltransferase...

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Détails bibliographiques
Publié dans:Biochem J
Auteurs principaux: Wu, Hong, Zheng, Weihong, Eram, Mohammad S., Vhuiyan, Mynol, Dong, Aiping, Zeng, Hong, He, Hao, Brown, Peter, Frankel, Adam, Vedadi, Masoud, Luo, Minkui, Min, Jinrong
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5280038/
https://ncbi.nlm.nih.gov/pubmed/27480107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160537
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