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Structural basis of arginine asymmetrical dimethylation by PRMT6
PRMT6 is a type I protein arginine methyltransferase, generating the asymmetric dimethylarginine mark on proteins such as histone H3R2. Asymmetric dimethylation of histone H3R2 by PRMT6 acts as a repressive mark that antagonizes trimethylation of H3 lysine 4 by the MLL histone H3K4 methyltransferase...
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| 發表在: | Biochem J |
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| Main Authors: | , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5280038/ https://ncbi.nlm.nih.gov/pubmed/27480107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20160537 |
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