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Structure and functional characterization of the atypical human kinase haspin
The protein kinase haspin/Gsg2 plays an important role in mitosis, where it specifically phosphorylates Thr-3 in histone H3 (H3T3). Its protein sequence is only weakly homologous to other protein kinases and lacks the highly conserved motifs normally required for kinase activity. Here we report stru...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2777956/ https://ncbi.nlm.nih.gov/pubmed/19918057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901989106 |
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