Structure-based screening of chemical libraries to identify small molecules that are likely to bind with the SET and RING-associated (SRA) domain of Ubiquitin-like, PHD and Ring Fi...

by Patnaik, Debasis
Published in BMC Res Notes (2020)

Genetic transformation of Indian bread (T. aestivum) and pasta (T. durum) wheat by particle bombardment of mature embryo-derived calli

by Patnaik, Debasis, Khurana, Paramjit
Published 2003

Targeting the SET and RING-associated (SRA) domain of ubiquitin-like, PHD and ring finger–containing 1 (UHRF1) for anti-cancer drug development

by Patnaik, Debasis, Estève, Pierre-Olivier, Pradhan, Sriharsa
Published in Oncotarget (2018)

Functional analysis of the N- and C-terminus of mammalian G9a histone H3 methyltransferase

by Estève, Pierre-Olivier, Patnaik, Debasis, Chin, Hang Gyeong, Benner, Jack, Teitell, Michael A., Pradhan, Sriharsa
Published 2005

Automethylation of G9a and its implication in wider substrate specificity and HP1 binding

by Chin, Hang Gyeong, Estève, Pierre-Olivier, Pradhan, Mihika, Benner, Jack, Patnaik, Debasis, Carey, Michael F., Pradhan, Sriharsa
Published 2007

Identification of Small Molecule Inhibitors of the Mitotic Kinase Haspin by High Throughput Screening using a Homogeneous Time-Resolved Fluorescence Resonance Energy Transfer Assay

by Patnaik, Debasis, Xian, Jun, Glicksman, Marcie A., Cuny, Gregory D., Stein, Ross L., Higgins, Jonathan M.G.
Published 2008

A Positive Feedback Loop Involving Haspin and Aurora B Promotes CPC Accumulation at Centromeres in Mitosis

by Wang, Fangwei, Ulyanova, Natalia P., van der Waal, Maike S., Patnaik, Debasis, Lens, Susanne M.A., Higgins, Jonathan M.G.
Published 2011

Structure and functional characterization of the atypical human kinase haspin

by Eswaran, Jeyanthy, Patnaik, Debasis, Filippakopoulos, Panagis, Wang, Fangwei, Stein, Ross L., Murray, James W., Higgins, Jonathan M. G., Knapp, Stefan
Published 2009

Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation

by Wang, Fangwei, Ulyanova, Natalia P., Daum, John R., Patnaik, Debasis, Kateneva, Anna V., Gorbsky, Gary J., Higgins, Jonathan M.G.
Published 2012

Dissecting Structure-Activity-Relationships of Crebinostat: Brain Penetrant HDAC Inhibitors for Neuroepigenetic Regulation

by Ghosh, Balaram, Zhao, Wen-Ning, Reis, Surya A., Patnaik, Debasis, Fass, Daniel M., Tsai, Li-Huei, Mazitschek, Ralph, Haggarty, Stephen J.
Published in Bioorg Med Chem Lett (2016)

Perturbation of Mitosis through Inhibition of Histone Acetyltransferases: The Key to Ochratoxin A Toxicity and Carcinogenicity?

by Czakai, Kristin, Müller, Katja, Mosesso, Pasquale, Pepe, Gaetano, Schulze, Markus, Gohla, Antje, Patnaik, Debasis, Dekant, Wolfgang, Higgins, Jonathan M.G., Mally, Angela
Published 2011

Brain-Penetrant LSD1 Inhibitors Can Block Memory Consolidation

by Neelamegam, Ramesh, Ricq, Emily L., Malvaez, Melissa, Patnaik, Debasis, Norton, Stephanie, Carlin, Stephen M., Hill, Ian T., Wood, Marcelo A., Haggarty, Stephen J., Hooker, Jacob M.
Published 2011

Phosphorylation of histone H3 at threonine 11 establishes a novel chromatin mark for transcriptional regulation

by Metzger, Eric, Yin, Na, Wissmann, Melanie, Kunowska, Natalia, Fischer, Kristin, Friedrichs, Nicolaus, Patnaik, Debasis, Higgins, Jonathan M.G., Potier, Noelle, Scheidtmann, Karl-Heinz, Buettner, Reinhard, Schüle, Roland
Published 2007

Dual histone H3 methylation marks at lysines 9 and 27 required for interaction with CHROMOMETHYLASE3

by Lindroth, Anders M, Shultis, David, Jasencakova, Zuzana, Fuchs, Jörg, Johnson, Lianna, Schubert, Daniel, Patnaik, Debasis, Pradhan, Sriharsa, Goodrich, Justin, Schubert, Ingo, Jenuwein, Thomas, Khorasanizadeh, Sepideh, Jacobsen, Steven E
Published 2004

Dual histone H3 methylation marks at lysines 9 and 27 required for interaction with CHROMOMETHYLASE3

by Lindroth, Anders M, Shultis, David, Jasencakova, Zuzana, Fuchs, Jörg, Johnson, Lianna, Schubert, Daniel, Patnaik, Debasis, Pradhan, Sriharsa, Goodrich, Justin, Schubert, Ingo, Jenuwein, Thomas, Khorasanizadeh, Sepideh, Jacobsen, Steven E
Published 2011

Structure-activity relationship study of beta-carboline derivatives as haspin kinase inhibitors

by Cuny, Gregory D., Ulyanova, Natalia P., Patnaik, Debasis, Liu, Ji-Feng, Lin, Xiangjie, Auerbach, Ken, Ray, Soumya S., Xian, Jun, Glicksman, Marcie A., Stein, Ross L., Higgins, Jonathan M.G.
Published 2012

Structure-activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors

by Cuny, Gregory D., Robin, Maxime, Ulyanova, Natalia P., Patnaik, Debasis, Pique, Valerie, Casano, Gilles, Liu, Ji-Feng, Lin, Xiangjie, Xian, Jun, Glicksman, Marcie A., Stein, Ross L., Higgins, Jonathan M.G.
Published 2010

Structure–activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors

by Cuny, Gregory D., Robin, Maxime, Ulyanova, Natalia P., Patnaik, Debasis, Pique, Valerie, Casano, Gilles, Liu, Ji-Feng, Lin, Xiangjie, Xian, Jun, Glicksman, Marcie A., Stein, Ross L., Higgins, Jonathan M. G.
Published 2010

Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models

by Silva, M Catarina, Ferguson, Fleur M, Cai, Quan, Donovan, Katherine A, Nandi, Ghata, Patnaik, Debasis, Zhang, Tinghu, Huang, Hai-Tsang, Lucente, Diane E, Dickerson, Bradford C, Mitchison, Timothy J, Fischer, Eric S, Gray, Nathanael S, Haggarty, Stephen J
Published in eLife (2019)

Development of [(18)F]Maleimide-Based Glycogen Synthase Kinase-3β Ligands for Positron Emission Tomography Imaging

by Hu, Kongzhen, Patnaik, Debasis, Collier, Thomas Lee, Lee, Katarzyna N., Gao, Han, Swoyer, Matthew R., Rotstein, Benjamin H., Krishnan, Hema S., Liang, Steven H., Wang, Jin, Yan, Zhiqiang, Hooker, Jacob M., Vasdev, Neil, Haggarty, Stephen J., Ngai, Ming-Yu
Published in ACS Med Chem Lett (2017)