MON-468 Selective Inhibition of Epigenetic Pathways Has Anti-Proliferative and Pro-Apoptotic Effects on the Mouse Corticotroph Tumor Cells, AtT20

Corticotrophinomas, which are neuroendocrine tumors (NETs) and represent >10% of all surgically removed pituitary adenomas, cause Cushing’s disease that is associated with hypersecretion of adrenocorticotropic hormone (ACTH) leading to excessive production of glucocorticoids by the adrenal cortex...

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Detalles Bibliográficos
Publicado en:J Endocr Soc
Autores principales: Lines, Kate, Stevenson, Mark, Filippakopoulos, Panagis, Muller, Susanne, Lockstone, Helen, Wright, Benjamin, Knapp, Stefan, Buck, David, Bountra, Chas, Thakker, Rajesh
Formato: Artigo
Lenguaje:Inglês
Publicado: Endocrine Society 2019
Materias:
Neuroendocrinology and Pituitary
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6551103/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-MON-468
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