Neuromedin B Receptor Antagonist Suppresses Pomc Expression in AtT-20 Cells and Human Corticotroph Adenoma Cells

Objective: We previously reported that Neuromedin B (NMB) is expressed in murine pituitary corticotrophs under adrenal insufficiency (1). Because NMB is also expressed in several cancer cells and stimulates ACTH secretion, we hypothesized that NMB is related to corticotroph adenoma cell proliferatio...

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Veröffentlicht in:J Endocr Soc
Hauptverfasser: Sekizaki, Tomonori, Kameda, Hiraku, Nakamura, Akinobu, Nomoto, Hiroshi, Cho, Kyu Yong, Ishi, Yukitomo, Motegi, Hiroaki, Miyoshi, Hideaki, Atsumi, Tatsuya
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2021
Schlagworte:
Neuroendocrinology and Pituitary
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8265901/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1113
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