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BETs inhibition attenuates oxidative stress and preserves muscle integrity in Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) affects 1 in 3500 live male births. To date, there is no effective cure for DMD, and the identification of novel molecular targets involved in disease progression is important to design more effective treatments and therapies to alleviate DMD symptoms. Here, we show...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Segatto, Marco, Szokoll, Roberta, Fittipaldi, Raffaella, Bottino, Cinzia, Nevi, Lorenzo, Mamchaoui, Kamel, Filippakopoulos, Panagis, Caretti, Giuseppina
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705749/
https://ncbi.nlm.nih.gov/pubmed/33257646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19839-x
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