Adenylosuccinic acid therapy ameliorates murine Duchenne Muscular Dystrophy

Arising from the ablation of the cytoskeletal protein dystrophin, Duchenne Muscular Dystrophy (DMD) is a debilitating and fatal skeletal muscle wasting disease underpinned by metabolic insufficiency. The inability to facilitate adequate energy production may impede calcium (Ca(2+)) buffering within,...

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Udgivet i:Sci Rep
Main Authors: Timpani, Cara A., Goodman, Craig A., Stathis, Christos G., White, Jason D., Mamchaoui, Kamel, Butler-Browne, Gillian, Gueven, Nuri, Hayes, Alan, Rybalka, Emma
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981178/
https://ncbi.nlm.nih.gov/pubmed/31980663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57610-w
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