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Crystal Structure and Inhibitor Identifications Reveal Targeting Opportunity for the Atypical MAPK Kinase ERK3

Extracellular signal-regulated kinase 3 (ERK3), known also as mitogen-activated protein kinase 6 (MAPK6), is an atypical member of MAPK kinase family, which has been poorly studied. Little is known regarding its function in biological processes, yet this atypical kinase has been suggested to play im...

詳細記述

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書誌詳細
出版年:Int J Mol Sci
主要な著者: Schröder, Martin, Filippakopoulos, Panagis, Schwalm, Martin P., Ferrer, Carla A., Drewry, David H., Knapp, Stefan, Chaikuad, Apirat
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7663056/
https://ncbi.nlm.nih.gov/pubmed/33114754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21217953
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