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Co-crystal structures of the protein kinase haspin with bisubstrate inhibitors

Haspin is a mitotic protein kinase that is responsible for the phosphorylation of Thr3 of histone H3, thereby creating a recognition motif for docking of the chromosomal passenger complex that is crucial for the progression of cell division. Here, two high-resolution models of haspin with previously...

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Dades bibliogràfiques
Publicat a:Acta Crystallogr F Struct Biol Commun
Autors principals: Lavogina, Darja, Kestav, Katrin, Chaikuad, Apirat, Heroven, Christina, Knapp, Stefan, Uri, Asko
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4854560/
https://ncbi.nlm.nih.gov/pubmed/27139824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X16004611
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