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Co-crystal structures of the protein kinase haspin with bisubstrate inhibitors
Haspin is a mitotic protein kinase that is responsible for the phosphorylation of Thr3 of histone H3, thereby creating a recognition motif for docking of the chromosomal passenger complex that is crucial for the progression of cell division. Here, two high-resolution models of haspin with previously...
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| Publicado en: | Acta Crystallogr F Struct Biol Commun |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
International Union of Crystallography
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4854560/ https://ncbi.nlm.nih.gov/pubmed/27139824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X16004611 |
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