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Selective inhibitors of Cyclin-G associated kinase (GAK) as anti-HCV agents
Cyclin-G associated kinase (GAK) emerged as a promising drug target for the treatment of viral infections. However, no potent and selective GAK inhibitors have been reported in the literature to date. This paper describes the discovery of isothiazolo[5,4-b]pyridines as selective GAK inhibitors, with...
שמור ב:
| הוצא לאור ב: | J Med Chem |
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| Main Authors: | , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4431592/ https://ncbi.nlm.nih.gov/pubmed/25822739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm501759m |
| תגים: |
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