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Discovery of a Novel Class of Covalent Dual Inhibitors Targeting the Protein Kinases BMX and BTK

The nonreceptor tyrosine TEC kinases are key regulators of the immune system and play a crucial role in the pathogenesis of diverse hematological malignancies. In contrast to the substantial efforts in inhibitor development for Bruton’s tyrosine kinase (BTK), specific inhibitors of the other TEC kin...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Int J Mol Sci
Päätekijät: Forster, Michael, Liang, Xiaojun Julia, Schröder, Martin, Gerstenecker, Stefan, Chaikuad, Apirat, Knapp, Stefan, Laufer, Stefan, Gehringer, Matthias
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7730235/
https://ncbi.nlm.nih.gov/pubmed/33291717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21239269
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