Dissecting the Role of BET Bromodomain Proteins BRD2 and BRD4 in Human NK Cell Function

Natural killer (NK) cells are innate lymphocytes that play a pivotal role in the immune surveillance and elimination of transformed or virally infected cells. Using a chemo-genetic approach, we identify BET bromodomain containing proteins BRD2 and BRD4 as central regulators of NK cell functions, inc...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Cribbs, Adam P., Filippakopoulos, Panagis, Philpott, Martin, Wells, Graham, Penn, Henry, Oerum, Henrik, Valge-Archer, Viia, Feldmann, Marc, Oppermann, Udo
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7953504/
https://ncbi.nlm.nih.gov/pubmed/33717143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.626255
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