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Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase
BTB-Kelch proteins form the largest subfamily of Cullin-RING E3 ligases, yet their substrate complexes are mapped and structurally characterized only for KEAP1 and KLHL3. KLHL20 is a related CUL3-dependent ubiquitin ligase linked to autophagy, cancer, and Alzheimer's disease that promotes the u...
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| Publicat a: | Structure |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cell Press
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6720452/ https://ncbi.nlm.nih.gov/pubmed/31279627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2019.06.005 |
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