β-Fluorofentanyls Are pH-Sensitive Mu Opioid Receptor Agonists

Por Rosas, Ricardo, Huang, Xi-Ping, Roth, Bryan L., Dockendorff, Chris
Publicado no ACS Med Chem Lett (2019)

Discovery and Characterization of Novel GPR39 Agonists Allosterically Modulated by Zinc

Por Sato, Seiji, Huang, Xi-Ping, Kroeze, Wesley K., Roth, Bryan L.
Publicado no Mol Pharmacol (2016)

Identification of Human Ether-à-go-go Related Gene Modulators by Three Screening Platforms in an Academic Drug-Discovery Setting

Por Huang, Xi-Ping, Mangano, Thomas, Hufeisen, Sandy, Setola, Vincent, Roth, Bryan L.
Publicado em 2010

Novel molecular targets of dezocine and their clinical implications

Por Liu, Renyu, Huang, Xi-Ping, Yeliseev, Alexei, Xi, Jin, Roth, Bryan L.
Publicado em 2014

Heterotropic Cooperativity within and between Protomers of an Oligomeric M(2) Muscarinic Receptor

Por Shivnaraine, Rabindra V., Huang, Xi-Ping, Seidenberg, Margaret, Ellis, John, Wells, James W.
Publicado em 2012

Roles of threonine 192 and asparagine 382 in agonist and antagonist interactions with M(1) muscarinic receptors

Por Huang, Xi-Ping, Nagy, Peter I, Williams, Frederick E, Peseckis, Steven M, Messer, William S
Publicado em 1999

Neurochemical Profiles of some novel psychoactive substances

Por Iversen, Les, Gibbons, Simon, Treble, Ric, Setola, Vincent, Huang, Xi-Ping, Roth, Bryan L.
Publicado em 2012

Exploring Halogen Bonds in 5-Hydroxytryptamine 2B Receptor–Ligand Interactions

Por Zhou, Yu, Wang, Yuanxun, Li, Pengfei, Huang, Xi-Ping, Qi, Xiangbin, Du, Yunfei, Huang, Niu
Publicado no ACS Med Chem Lett (2018)

Molecular interactions between general anesthetics and the 5HT(2B) receptor

Por Matsunaga, Felipe, Gao, Lu, Huang, Xi-Ping, Saven, Jeffery G., Roth, Bryan L., Liu, Renyu
Publicado no J Biomol Struct Dyn (2013)

The Development, Validation, and Use of Quantitative Structure Activity Relationship Models of 5-Hydroxytryptamine (2B) Receptor Ligands to Identify Novel Receptor Binders and Puta...

Por Hajjo, Rima, Grulke, Christopher, Golbraikh, Alexander, Setola, Vincent, Huang, Xi-Ping, Roth, Bryan L., Tropsha, Alexander
Publicado em 2010

The Ketamine Analogue Methoxetamine and 3- and 4-Methoxy Analogues of Phencyclidine Are High Affinity and Selective Ligands for the Glutamate NMDA Receptor

Por Roth, Bryan L., Gibbons, Simon, Arunotayanun, Warunya, Huang, Xi-Ping, Setola, Vincent, Treble, Ric, Iversen, Les
Publicado em 2013

The First Structure–Activity Relationship Studies for Designer Receptors Exclusively Activated by Designer Drugs

Por Chen, Xin, Choo, Hyunah, Huang, Xi-Ping, Yang, Xiaobao, Stone, Orrin, Roth, Bryan L., Jin, Jian
Publicado no ACS Chem Neurosci (2015)

Correction: The Ketamine Analogue Methoxetamine and 3- and 4-Methoxy Analogues of Phencyclidine Are High Affinity and Selective Ligands for the Glutamate NMDA Receptor

Por Roth, Bryan L., Gibbons, Simon, Arunotayanun, Warunya, Huang, Xi-Ping, Setola, Vincent, Treble, Ric, Iversen, Les
Publicado no PLoS One (2018)

The marine algal toxin azaspiracid is an open state blocker of hERG potassium channels

Por Twiner, Michael J., Doucette, Gregory J., Rasky, Andrew, Huang, Xi-Ping, Roth, Bryan L., Sanguinetti, Michael C.
Publicado em 2012

trans-2-(2,5-Dimethoxy-4-iodophenyl)cyclopropylamine and trans-2-(2,5-dimethoxy-4-bromophenyl)cyclopropylamine as potent agonists for the 5-HT(2) receptor family

Por Pigott, Adam, Frescas, Stewart, McCorvy, John D, Huang, Xi-Ping, Roth, Bryan L, Nichols, David E
Publicado em 2012

D(1)-D(2) Dopamine Receptor Synergy Promotes Calcium Signaling via Multiple Mechanisms

Por Chun, Lani S., Free, R. Benjamin, Doyle, Trevor B., Huang, Xi-Ping, Rankin, Michele L., Sibley, David R.
Publicado em 2013

A simple representation of three-dimensional molecular structure

Por Axen, Seth D., Huang, Xi-Ping, Cáceres, Elena L., Gendelev, Leo, Roth, Bryan L., Keiser, Michael J.
Publicado no J Med Chem (2017)

Amisulpride is a potent 5-HT(7) antagonist: relevance for antidepressant actions in vivo

Por Abbas, Atheir I., Hedlund, Peter B., Huang, Xi-Ping, Tran, Thuy B., Meltzer, Herbert Y., Roth, Bryan L.
Publicado em 2009

Selectivity Challenges in Docking Screens for GPCR Targets and Antitargets

Por Weiss, Dahlia R., Karpiak, Joel, Huang, Xi-Ping, Sassano, Maria F., Lyu, Jiankun, Roth, Bryan L., Shoichet, Brian K.
Publicado no J Med Chem (2018)

Design, Synthesis, and Characterization of Ogerin-Based Positive Allosteric Modulators for G Protein-Coupled Receptor 68 (GPR68)

Por Yu, Xufen, Huang, Xi-Ping, Kenakin, Terry P., Slocum, Samuel T., Chen, Xin, Martini, Michael L., Liu, Jing, Jin, Jian
Publicado no J Med Chem (2019)