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Heterotropic Cooperativity within and between Protomers of an Oligomeric M(2) Muscarinic Receptor
At least four allosteric sites have been found to mediate the dose-dependent effects of gallamine on the binding of [(3)H]quinuclidinylbenzilate (QNB) and N-[(3)H]methylscopolamine (NMS) to M(2) muscarinic receptors in membranes and solubilized preparations from porcine atria, CHO cells, and Sf9 cel...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3595096/ https://ncbi.nlm.nih.gov/pubmed/22551249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3000287 |
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