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Roles of threonine 192 and asparagine 382 in agonist and antagonist interactions with M(1) muscarinic receptors

1. Conserved amino acids, such as Thr in transmembrane domains (TM) V and Asn in TM VI of muscarinic receptors, may be important in agonist binding and/or receptor activation. In order to determine the functional roles of Thr192 and Asn382 in human M(1) receptors in ligand binding and receptor activ...

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Bibliografische gegevens
Hoofdauteurs: Huang, Xi-Ping, Nagy, Peter I, Williams, Frederick E, Peseckis, Steven M, Messer, William S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1999
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565834/
https://ncbi.nlm.nih.gov/pubmed/10188986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702301
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