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Muscarinic Cholinergic Receptor Agonist and Peripheral Antagonist for Schizophrenia
BACKGROUND: The muscarinic receptor agonist xanomeline has antipsychotic properties and is devoid of dopamine receptor–blocking activity but causes cholinergic adverse events. Trospium is a peripherally restricted muscarinic receptor antagonist that reduces peripheral cholinergic effects of xanomeli...
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| Publicat a: | N Engl J Med |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7610870/ https://ncbi.nlm.nih.gov/pubmed/33626254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa2017015 |
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