T106. KARXT: A M1/M4 PREFERRING MUSCARINIC AGONIST FOR THE TREATMENT OF SCHIZOPHRENIA

BACKGROUND: Xanomeline is a M1 /M4 preferring muscarinic agonist that has demonstrated antipsychotic and pro-cognitive effects in both schizophrenia (Shekar, et al, 2008) and Alzheimer’s disease (Bodick et al, 1997). However, its peripheral cholinergic side effects, including nausea, vomiting and di...

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Vydáno v:Schizophr Bull
Hlavní autoři: Brannan, Stephen, Miller, Andrew, Felder, Christian, Paul, Steven, Breier, Alan
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Poster Session I
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6455874/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbz019.386
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