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T106. KARXT: A M1/M4 PREFERRING MUSCARINIC AGONIST FOR THE TREATMENT OF SCHIZOPHRENIA
BACKGROUND: Xanomeline is a M1 /M4 preferring muscarinic agonist that has demonstrated antipsychotic and pro-cognitive effects in both schizophrenia (Shekar, et al, 2008) and Alzheimer’s disease (Bodick et al, 1997). However, its peripheral cholinergic side effects, including nausea, vomiting and di...
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| Publicado en: | Schizophr Bull |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6455874/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbz019.386 |
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