A carregar...
Selectivity Challenges in Docking Screens for GPCR Targets and Antitargets
[Image: see text] To investigate large library docking’s ability to find molecules with joint activity against on-targets and selectivity versus antitargets, the dopamine D(2) and serotonin 5-HT(2A) receptors were targeted, seeking selectivity against the histamine H(1) receptor. In a second campaig...
Na minha lista:
| Publicado no: | J Med Chem |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2018
|
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6105036/ https://ncbi.nlm.nih.gov/pubmed/29990431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.8b00718 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|